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CAS 3786-08-1: N-Acetyl-L-phenylalanyl-3,5-diiodo-L-tyrosine

Formula:C20H20I2N2O5
InChI:InChI=1S/C20H20I2N2O5/c1-11(25)23-16(9-12-5-3-2-4-6-12)19(27)24-17(20(28)29)10-13-7-14(21)18(26)15(22)8-13/h2-8,16-17,26H,9-10H2,1H3,(H,23,25)(H,24,27)(H,28,29)/t16-,17-/m0/s1
InChI key:InChIKey=DWIHCEZUWCRUES-IRXDYDNUSA-N
SMILES:C([C@H](NC([C@H](CC1=CC=CC=C1)NC(C)=O)=O)C(O)=O)C2=CC(I)=C(O)C(I)=C2
Synonyms:
  • (2S)-2-[(N-acetyl-L-phenylalanyl)amino]-3-(4-hydroxy-3,5-diiodophenyl)propanoate
  • <span class="text-smallcaps">L</smallcap>-Tyrosine, N-(N-acetyl-<smallcap>L</span>-phenylalanyl)-3,5-diiodo-
  • <span class="text-smallcaps">L</smallcap>-Tyrosine, N-acetyl-<smallcap>L</span>-phenylalanyl-3,5-diiodo-
  • Acetyl-<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-diiodotyrosine
  • N-Acetyl-<span class="text-smallcaps">L</smallcap>-phenylalanyl-3,5-diiodo-<smallcap>L</span>-tyrosine
  • N-Acetyl-<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-3,5-diiodotyrosine
  • N-Acetyl-<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-diiodotyrosine
  • N-Acetylphenylalanyl-3,5-diiodotyrosine
  • N-acetyl-L-phenylalanyl-3,5-diiodo-L-tyrosine
  • Nsc 334284
  • Tyrosine, N-(N-acetyl-3-phenyl-<span class="text-smallcaps">L</smallcap>-alanyl)-3,5-diiodo-, <smallcap>L</span>-
  • See more synonyms
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Found 1 products.
  • Ac-Phe-3,5-diI-Tyr-OH
    Biosynth
    + Info

    Ac-Phe-3,5-diI-Tyr-OH

    CAS:
    Ac-Phe-3,5-diI-Tyr-OH is a synthetic substrate that is an inhibitor molecule. It inhibits the proteolytic activity of pepsin and trypsin, which are enzymes secreted by the stomach to break down food. Ac-Phe-3,5-diI-Tyr-OH has been shown to inhibit the production of human serum amyloid A (HSA) in vitro. This molecule has a pH optimum of 8 and can be activated by acidic conditions. This compound contains a disulfide bond, which is necessary for the active site cleft in this type of enzyme inhibitor. The sequence may represent an enzyme inhibitor with a novel mechanism of action that has not been reported before.
    Formula:C20H20I2N2O5
    Purity:Min. 95%
    Molecular weight:622.19 g/mol

    Ref: 3D-FA47656

    250mg
    Discontinued
    Discontinued product