CAS: 3811-15-2

Picropodophyllol

Picropodophyllol is a natural product isolated from the roots of Dysosma versipellis

Picropodophyllol is a type of lignan, which is a class of natural products derived from the phenylpropanoid pathway, primarily sourced from plants such as the roots and rhizomes of the Podophyllum species. It exhibits its biological activity through the inhibition of microtubule formation, which is a key process in cell division. By disrupting microtubule assembly, Picropodophyllol effectively halts cell proliferation, making it a compound of interest in anti-cancer research and the development of chemotherapeutic agents. The primary application of Picropodophyllol is in the field of medicinal chemistry, where it is utilized as a lead compound or scaffold in the synthesis of more potent and selective analogs. Its antimitotic properties have also made it a subject of study in the treatment of a variety of cancers. Research into its derivatives seeks to enhance efficacy and reduce potential side effects, further underscoring its relevance in pharmaceutical and biochemical research.