CAS: 38170-02-4

2-Hydroxy-4-iodobenzaldehyde is an intermediate in the synthesis of a variety of pharmacologic agents. It can be synthesized by a cross-coupling reaction from 2-chloro-4,5-dimethoxybenzaldehyde and iodomethane. This compound can be immobilized on a solid support for use in Suzuki coupling reactions. 2-Hydroxy-4-iodobenzaldehyde has been used as a reagent for the preparation of nitro, proton, amines, and intramolecular hydrogen compounds. The cytosolic enzyme carbonic anhydrase catalyzes the conversion of CO2 to bicarbonate ion (HCO3-) and H+. The fluorescence properties of this compound have been characterized using fluorescent compounds and optical properties such as its emission spectrum.

2-Hydroxy-4-iodo-benzaldehyde

Applications 2-hydroxy-4-iodobenzaldehyde is used in the preparation of anti-B7-H3 antibodies. References Benatuil, Lorenzo. et al., PCT Int. Appl. (2017);