Methyl 3-(methylnitrosoamino)propanoate, identified by its CAS number 383417-47-8, is a chemical compound that belongs to the class of nitrosamines, which are known for their potential carcinogenic properties. This substance features a methyl ester functional group, which contributes to its reactivity and solubility in organic solvents. The presence of the nitrosoamino group indicates that it may participate in various chemical reactions, including those involving nucleophilic attack and electrophilic substitution. Methyl 3-(methylnitrosoamino)propanoate is typically synthesized through specific chemical reactions involving nitrosation processes. Due to its structural characteristics, it may exhibit biological activity, and studies have suggested that nitrosamines can be formed from dietary sources or during the metabolism of certain compounds. Safety precautions are essential when handling this substance, as nitrosamines are often associated with health risks, including cancer. Proper storage and disposal methods should be followed to mitigate any potential hazards.

Methyl 3-(methylnitrosoamino)propanoate

383417-47-8: Propanoic acid, 3-(methylnitrosoamino)-, methyl ester, Methyl 3-(methylnitrosoamino)propanoate, β-Alanine, N-methyl-N-nitroso-, methyl ester

N-Nitroso-N-methyl-3-aminopropionic acid, methyl ester (NMPA) is a carcinogen that is used in the production of butyric acid. NMPA can induce tumors when injected into the liver and lungs of rats. It has also been shown to induce tumorigenesis in the colon, small intestine, and kidney of mice. NMPA is metabolized by decarboxylation to produce n-nitrososarcosine, which damages DNA and inhibits DNA repair. NMPA binds covalently to proteins, forming amino nitroso compounds. These compounds are likely responsible for NMPA's tumorigenic effects.

N-Nitroso-N-methyl-3-aminopropionic acid, methyl ester

Applications The methyl ester of the N-nitrosamino acid, N-nitroso-N-methylaminopropionic acid isolated from various tobacco products. The occurence of N-nitrosamino acids such as N-nitroso-N-methylaminopropionic acid, is highly correlated with levels of tobacco-specific-nitrosamines, highly volatile, carcinogenic compounds.
 Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ohshima, H., et al.: Cancer Lett., 26, 153, (1985)


CAS 383417-47-8: Methyl 3-(methylnitrosoamino)propanoate

N-Nitroso-N-methyl-3-aminopropionic acid, methyl ester

Ref: 3D-FN26378

N-Nitroso-N-methyl-3-aminopropionic Acid, Methyl Ester

Ref: TR-N529250