CAS: 3864-50-4

Applications Dexamethasone 23-Dimorpholinophosphinate-D5 is an intermediate in the synthesis of Dexamethasone Phosphate-D5 (Major) (D298837), which is the labeled form of Dexamethasone Phosphate (D298835), which is the pro-drug of Dexamethasone (D298800), an anti-inflammatory glucocorticoid. It was found that liposomal DXM-P inhibited both chronic inflammation and joint destruction, whereas free DXM-P failed to prevent joint destruction. References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),

Applications Dexamethasone 23-Dimorpholinophosphinate is an intermediate in the synthesis of Dexamethasone Phosphate (D298835), the pro-drug of Dexamethasone (D298800), an anti-inflammatory glucocorticoid. References Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),