CAS 38693-08-2: 2-Chloro-1-(2-methyl-1H-indol-3-yl)ethanone

2-Chloro-1-(2-methyl-1H-indol-3-yl)-1-ethanone (CAS: 103873-34-5) is a quinoline derivative. It is the most selective inhibitor of indoleamine 2,3 dioxygenase (IDO) to date. Caffeine, an indole, is converted into 2,3-dihydroxyphenylalanine (DOPA), which can be converted into dopamine and norepinephrine by DOPA decarboxylase. Quinoline compounds are also used in the synthesis of isatin, which is an aromatic heterocycle with two double bonds. Isatin can be transformed into hydrazines through a series of reactions. Indoles are present in coal tar and are produced by the oxidation of phenylalanine. They are also found in plant sources such as cumin seeds or black pepper.