The chemical substance known as "2H-Purin-2-one, 6-amino-9-β-D-arabinofuranosyl-1,9-dihydro-" with the CAS number 38819-11-3 is a nucleoside analog, specifically a derivative of purine. This compound features a purine base structure, which is characterized by a fused double-ring system containing nitrogen atoms. The presence of the 6-amino group enhances its biological activity, making it relevant in the context of antiviral and anticancer research. The β-D-arabinofuranosyl moiety indicates that the sugar component is in the β-anomeric configuration, which is crucial for its interaction with nucleic acid synthesis pathways. This compound is typically soluble in polar solvents and may exhibit specific optical activity due to its chiral centers. Its structural characteristics allow it to mimic natural nucleosides, potentially interfering with nucleic acid metabolism in various biological systems. Overall, this substance is of significant interest in medicinal chemistry and pharmacology for its potential therapeutic applications.

2H-Purin-2-one, 6-amino-9-β-D-arabinofuranosyl-1,9-dihydro-

38819-11-3: 2H-Purin-2-one, 6-amino-9-β-D-arabinofuranosyl-1,9-dihydro-, 2-Hydroxy-6-amino-9-(β-D-arabinofuranosyl)purine, 6-Amino-2-hydroxy-9-(β-D-arabinofuranosyl)-purine

9-(b-D-Arabinofuranosyl)isoguanine is a modified nucleoside that has antiviral activity. It is synthesized by substituting the 2'-hydroxyl group of deoxyribose with an arabinofuranose, which can be phosphorylated to form 9-(b-D-arabinofuranosyl)isoguanine 5'-monophosphate. This novel antiviral agent inhibits the synthesis of viral DNA and RNA, and is effective against a wide range of viruses in vitro. The drug was shown to have anticancer activities in animal models and has been patented for use as a chemotherapeutic agent against leukemia, lymphoma, and other cancers.

CAS 38819-11-3: 2H-Purin-2-one, 6-amino-9-β-D-arabinofuranosyl-1,9-dihydro-

9-(b-D-Arabinofuranosyl)isoguanine

Ref: 3D-NA09573