2-(Acetyloxy)propanoyl chloride, with the CAS number 38939-83-2, is an organic compound characterized by its acyl chloride functional group, which is known for its reactivity and ability to form esters and amides. This compound features an acetyloxy group, indicating the presence of an acetyl moiety attached to a propanoyl chloride structure. It is typically a colorless to pale yellow liquid with a pungent odor, characteristic of acyl chlorides. The compound is soluble in organic solvents such as dichloromethane and ether but reacts vigorously with water, producing hydrochloric acid and the corresponding carboxylic acid. Due to its reactivity, it is often used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. Safety precautions are essential when handling this compound, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper storage in a cool, dry place away from moisture is also crucial to maintain its stability and prevent hydrolysis.

2-(Acetyloxy)propanoyl chloride

38939-83-2: 1-Chloro-1-oxopropan-2-yl acetate, 2-(Acetyloxy)propanoyl chloride, 2-Acetoxypropanoyl chloride, 2-Acetoxypropionyl chloride, 2-Chloro-1-Methyl-2-Oxoethyl Acetate, <span class="text-smallcaps">DL</span>-2-Acetoxypropionyl chloride, Lactoyl chloride, acetate, O-Acetyllactyl chloride, Propanoyl Chloride, 2-(Acetyloxy)-, α-Acetoxypropionyl chloride

2-Acetoxypropionyl chloride is a chlorinating agent that can be used to produce sulfides, thiosulfates, and sulfones. It is a colorless gas with a pungent odor. 2-Acetoxypropionyl chloride can also be used as an intermediate in the synthesis of aziridines and aziridinium salts. The enantiomer of this agent is called acetoxypropionate chloride. It has been shown to react with triphosgene to form chloroformates and chloroacetates, which are useful intermediates in organic synthesis. The sequence of reactions for the preparation of 2-acetoxypropionyl chloride from sodium sulfide is as follows: 

1) Sodium Sulfide + Chlorine Gas -> Sodium Chloride + Sulfur Dioxide 
2) Sodium Chloride + Potassium Acetate -> Potassium Chloride + Sodium Acetate

CAS 38939-83-2: 2-(Acetyloxy)propanoyl chloride

2-Acetoxypropionyl Chloride

Ref: 3D-NBA93983

2-Acetoxypropionyl Chloride

Ref: 3B-A2932

2-Acetoxypropionylchloride

Ref: IN-DA00CHJM