CAS 39098-97-0: 2-Thiopheneacetyl chloride

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Thiophene-2-acetyl chloride is a benzimidazole compound and an antimicrobial agent. The optimum concentration of this compound is 0.5-1.0 mM, but it has been found to be active at concentrations as low as 0.001 mM. Thiophene-2-acetyl chloride inhibits the growth of bacteria by binding to their receptors and preventing the binding of essential nutrients such as amino acids, nucleotides, and cofactors. This drug also prevents the formation of intracellular hydrogen peroxide by inhibiting the enzyme heme oxygenase and has anti-HIV activity.

2-Thiopheneacetyl chloride was used in the synthesis of (S)-ethyl-1-(2-thiopheneacetyl)-3-piperidinecarboxylate, nipecotate-containing immunopotentiator, 5-fluorouracil-cephalosporin prodrug, series of new N,N-di(thiopheneacetyl)diamines derivatives and 6-β-(thiophen-2-yl)acetamidomorphine. Also used in the synthesis of Nitrocefin. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

(Thien-2-yl)acetyl chloride