Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate, identified by the CAS number 391-02-6, is a chemical compound belonging to the quinoline family, which is characterized by a bicyclic structure containing a benzene ring fused to a pyridine ring. This compound features a trifluoromethyl group, which enhances its lipophilicity and may influence its biological activity. The presence of a hydroxyl group contributes to its potential as a hydrogen bond donor, while the ethyl ester moiety can affect its solubility and reactivity. Quinoline derivatives are often studied for their pharmacological properties, including antimicrobial and antitumor activities. The trifluoromethyl group is known to impart unique electronic properties, making such compounds of interest in medicinal chemistry. Additionally, the compound's stability, reactivity, and interactions with biological targets can be influenced by its functional groups, making it a subject of research in various fields, including drug development and materials science.

ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarb

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Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate

ETHYL 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE

Ethyl 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate is an isomeric, hydroxylamine and chloride salt of the heterocyclic compound ethyl 7-(trifluoromethyl)quinoline-3-carboxylate. The hydroxylamine moiety of the molecule has shown to be cytotoxic against human colorectal carcinoma cells (HCT 116), with a potency similar to that of 5FU. In addition, hydroxylamine has been shown to induce apoptosis in cancer cell lines, which may be due to its ability to inhibit DNA synthesis and protein synthesis.

CAS 391-02-6: ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarb

Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate

Ref: 54-PC9494

ETHYL 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE

Ref: IN-DA00CK5Z

Ethyl 4-Hydroxy-7-(Trifluoromethyl)Quinoline-3-Carboxylate

Ref: 3D-FE95459