CAS 3938-96-3: Ethyl 2-methoxyacetate

Ethyl methoxyacetate was used as acyl donor during the preparation of enantiomers of several phenylethylamines, as acylation reagent for the aminolysis of 1-phenylethanamine and used in an industrial, lipase-catalyzed kinetic resolution of primary amine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ethyl methoxyacetate

Ethyl 2-methoxyacetate is an organic compound that is a derivative of ethylene diamine. It can be produced by the addition of hydrochloric acid to methyl acetate or by the reaction of methylamine and ethylene diamine. The kinetics of this reaction have been studied in detail and it has been found that the formation of ethyl 2-methoxyacetate is highly dependent on temperature and pressure, with the rate increasing as temperature increases. This product is typically used for chemical reactions such as esterification, saponification, oxidation, and reduction. Isolated yields are typically high for this product, with a sample preparation time of less than one hour. Ethyl 2-methoxyacetate has a hydroxyl group that can react with amines to form amides or imides. It also reacts with methyl ethyl ketone to produce methyl 3-hydroxypropanoate.