CAS 39620-02-5: 5-Bromonicotinoyl chloride
Formula:C6H3BrClNO
InChI:InChI=1/C6H3BrClNO/c7-5-1-4(6(8)10)2-9-3-5/h1-3H
SMILES:c1c(cncc1Br)C(=O)Cl
Synonyms:- 5-Bromopyridine-3-carbonyl chloride
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Found 6 products.
5-BROMONICOTINOYL CHLORIDE
CAS:Formula:C6H3BrClNOPurity:97%Color and Shape:SolidMolecular weight:220.451119999999975-Bromonicotinoyl chloride
CAS:5-Bromonicotinoyl chlorideFormula:C6H3BrClNOPurity:By gc: 99.4% by area (Typical Value in Batch COA)Color and Shape: white crystalline powderMolecular weight:220.45g/mol5-Bromonicotinoyl chloride
CAS:5-Bromonicotinoyl chloride is a synthetic compound that has been shown to be an inhibitor of some cancer cells. This compound has been shown to inhibit the enzyme phosphatidylinositol 3-kinase (PI3K) in a specific ligand-dependent manner. The precise mechanism of action is not yet understood, but it is thought that 5-bromonicotinoyl chloride may bind to the enzyme and inhibit its activity by hydrogen bonding interactions. This product inhibits PI3K, which is responsible for generating phosphatidylinositol 3,4,5-triphosphate (PIP3). PIP3 activates protein kinase B (AKT), which promotes cell proliferation and inhibits apoptosis. It also inhibits the enzyme phosphodiesterase type 4 (PDE4), which controls intracellular levels of cyclic GMP. PDE4 activity leads to vasodilation and platelet aggregation.Formula:C6H3BrClNO2Purity:Min. 95%Molecular weight:236.54 g/mol
