Trimethylsilyl trifluoroacetate (TMS-TFA) is a chemical compound characterized by its unique structure, which includes a trimethylsilyl group and a trifluoroacetate moiety. It is typically a colorless to pale yellow liquid with a distinctive odor. TMS-TFA is known for its role as a derivatizing agent in organic synthesis and analytical chemistry, particularly in gas chromatography and mass spectrometry. The presence of the trifluoroacetate group enhances the volatility and stability of the compounds it derivatizes, making them easier to analyze. Additionally, the trimethylsilyl group improves the solubility of polar compounds in non-polar solvents. TMS-TFA is generally stable under standard conditions but should be handled with care due to its reactivity with water and potential to release trifluoroacetic acid upon hydrolysis. It is important to use appropriate safety measures, including personal protective equipment, when working with this compound due to its potential health hazards.

Trimethylsilyl trifluoroacetate

400-53-3: (Trifluoroacetoxy)trimethylsilane, Acetic acid, 2,2,2-trifluoro-, trimethylsilyl ester, Acetic acid, trifluoro-, trimethylsilyl ester, Silanol, trimethyl-, trifluoroacetate, Trimethyl(trifluoroacetato)silane, Trimethyl(trifluoroacetoxy)silane, Trimethylsilyltrifluoroacetate, Trimethylsilyl trifluoroacetate

CAS 400-53-3: Trimethylsilyl trifluoroacetate

TRIMETHYLSILYL TRIFLUOROACETATE

Ref: 3H-SIT8618.0

Trimethylsilyl trifluoroacetate

Ref: 54-PC8977

Trimethylsilyl-trifluoroacetate

Ref: 10-S20360

TRIMETHYLSILYL TRIFLUOROACETATE

Ref: IN-DA003V4I

Trimethylsilyl Trifluoroacetate

Ref: 3B-T2629