CAS 402-49-3: 4-(Trifluoromethyl)benzyl bromide
Formula:C8H6BrF3
InChI:InChI=1S/C8H6BrF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2
InChI key:InChIKey=IKSNDOVDVVPSMA-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C1=CC=C(CBr)C=C1
Synonyms:- 1-Trifluoromethyl-4-(bromomethyl)benzene
- 4-(Trifluoromethyl)Benzyl Bromide
- 4-Bromomethylbenzotrifluoride
- 4-Trifluoromethylbenzyl Bromide
- Benzene, 1-(bromomethyl)-4-(trifluoromethyl)-
- p-(Trifluoromethyl)benzyl bromide
- p-Xylene, α′-bromo-α,α,α-trifluoro-
- α′-Bromo-α,α,α-trifluoro-p-xylene
- 1-(Bromomethyl)-4-(trifluoromethyl)benzene
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Found 8 products.
4-(Trifluoromethyl)benzyl bromide
CAS:4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond.Formula:C8H6BrF3Purity:Min. 95%Color and Shape:White PowderMolecular weight:239.03 g/mol4-(Trifluoromethyl)benzyl bromide, 98%
CAS:4-(Trifluoromethyl)benzyl bromide can be used to produce p-trifluoromethylbenzyl phenyl sulfide. It is used in medicine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C8H6BrF3Purity:98%Color and Shape:Crystals or powder or crystalline powder or fused solid, White to creamMolecular weight:239.044-(Trifluoromethyl)benzyl Bromide
CAS:Controlled ProductApplications 4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Porcari, A., et al.: J. Med. Chem., 41, 1252 (1998); Ishida, T., et al.: Bioorg. Med. Chem. Lett., 16, 1859 (2006)Formula:C8H6BrF3Color and Shape:NeatMolecular weight:239.034-(Trifluoromethyl)Benzyl Bromide
CAS:Formula:C8H6BrF3Purity:98%Color and Shape:SolidMolecular weight:239.03244-(Trifluoromethyl)benzyl bromide
CAS:4-(Trifluoromethyl)benzyl bromideFormula:C8H6BrF3Purity:98%Color and Shape: white to off white fused solidMolecular weight:239.03g/mol4-(Trifluoromethyl)benzyl Bromide
CAS:Formula:C8H6BrF3Purity:>98.0%(GC)Color and Shape:White or Colorless to Light yellow powder to lump to clear liquidMolecular weight:239.044-(Trifluoromethyl)benzyl bromide
CAS:Purity:98.0%Color and Shape:Low Melting SolidMolecular weight:239.03500366210938α'-Bromo-α,α,α-trifluoro-p-xylene, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C8H6BrF3Purity:98%Color and Shape:White to light yellow, Low melting crystalline solidMolecular weight:239.04
