CAS 402-71-1: Nα-Tosyl-L-phenylalanine chloromethyl ketone
Formula:C17H18ClNO3S
InChI:InChI=1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1
InChI key:InChIKey=MQUQNUAYKLCRME-INIZCTEOSA-N
SMILES:[C@H](NS(=O)(=O)C1=CC=C(C)C=C1)(CC2=CC=CC=C2)C(CCl)=O
Synonyms:- (S)-N-(4-Chloro-3-oxo-1-phenylbutan-2-yl)-4-methylbenzenesulfonamide
- <span class="text-smallcaps">L</span>-1-Chloro-3-tosylamidyl-4-phenyl-2-butanone
- <span class="text-smallcaps">L</span>-1-Chloro-4-phenyl-3-p-tolylsulfonamidobutan-2-one
- <span class="text-smallcaps">L</span>-1-Chloro-4-phenyl-3-toluene-p-sulfonamido-2-butanone
- <span class="text-smallcaps">L</span>-1-Tosylamide-2-phenylethylchloromethyl ketone
- <span class="text-smallcaps">L</span>-1-Tosylamido-2-phenylethyl chloromethyl ketone
- <span class="text-smallcaps">L</span>-Tolylsulfonylphenylalanyl chloromethyl ketone
- Benzenesulfonamide, N-((1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-
- Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)-
- Brn 2895215
- L-1-Tosylamido-2-phenylethyl chloromethyl ketone
- See more synonyms
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Found 8 products.
N-p-Tosyl-L-phenylalanine chloromethyl ketone
CAS:Formula:C17H18ClNO3SPurity:(TLC) ≥ 98.0%Color and Shape:White to off-white powderMolecular weight:351.85Benzenesulfonamide,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl-
CAS:Formula:C17H18ClNO3SPurity:97%Color and Shape:SolidMolecular weight:351.8477N-α-Tosyl-L-phenylalanylchloromethane
CAS:Controlled ProductApplications N-α-Tosyl-L-phenylalanylchloromethane is a proteinase inhibitors with apoptotic function. Studies have shown that it induces caspase-dependent apoptosis in Epstein-Barr virus (EBV)-transformed human B cell lines with release of pro-apoptotic proteins from mitochondria. It also results in down-regulation of the anti-apoptotic proteins and caspase-dependent cleavage of two anti-apoptotic proteins. It promotes dephosphorylation of p53 on serine residues. References Jitkaew, S. et al.: J. Bio. Chem., 284, 27827 (2009); Kim, K. et al.: Biochem. Biophys. Res. Comm., 306, 954 (2003); Griscavage, J. et al.: Biochem. Biophys. Res. Comm., 215, 721 (1995)Formula:C17H18ClNO3SColor and Shape:NeatMolecular weight:351.848Tos-Phe-chloromethylketone
CAS:TPCK irreversibly inhibits α-chymotrypsin, chymotrypsin-like serine proteases, and several cysteine proteases. Additionally, TPCK was shown to affect physiological events as proliferation and apoptosis in certain systems.Formula:C17H18ClNO3SPurity:> 98%Color and Shape:White PowderMolecular weight:351.85L-1-4'-Tosylamino-2-phenylethyl chloromethyl ketone, 99+%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C17H18ClNO3SPurity:99+%Color and Shape:Crystalline powder, WhiteMolecular weight:351.85TPCK
CAS:TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesisFormula:C17H18ClNO3SPurity:97.33%Color and Shape:PowderMolecular weight:351.85N-Tosyl-L-phenylalanine chloromethyl ketone
CAS:N-Tosyl-L-phenylalanine chloromethyl ketone is a chloromethyl ketone that is used to synthesize the Toll-like receptor 3 (TLR3) ligand, peptide 2. N-Tosyl-L-phenylalanine chloromethyl ketone has been shown to have antiviral activity against influenza virus. It binds to the DNA of the virus, preventing infection and replication. It also has antiinflammatory and insecticidal properties.Formula:C17H18ClNO3SPurity:Min. 95%Molecular weight:351.85 g/mol
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