CAS 4039-92-3: Benzene, 1-(chloromethyl)-4-phenoxy-

1-(Chloromethyl)-4-Phenoxybenzene

1-(Chloromethyl)-4-phenoxybenzene (1-CPB) is a nucleophilic reagent that is used in the synthesis of pleuromutilin derivatives. 1-CPB reacts with chlorides to form chloroalkylphenols, which are then hydrolyzed to yield phenolic acids. The reaction mechanism involves nucleophilic substitution at the electrophilic carbon atom of the chlorine molecule, followed by an elimination reaction with chloride. 1-CPB can also react with halides and thionyl chloride to form chloroalkylphenols. This substance has been shown to be effective in treating tuberculosis and other mycobacterial diseases.