CAS 4100-41-8: 1,2,3-Thiadiazol-5-amine

Applications 5-Amino-1,2,3-thiadiazole, as a thiadiazole derivative, is a privileged structure in medicinal chemistry and has been investigated for anticonvulsant and antimicrobial activities. References Matsumoto, T., et al.: Masakuni; PCT Int. Appl. (2006), WO 2006054652 A1 20060526; Gommaa, A., et al.: Alexandria J. Pharm. Sci., 5, 153 (1991)

1,2,3-Thiadiazol-5-amine

5-Amino-1,2,3-anilidothiobiazole is a trifluoride that is prepared by the reaction of hydrochloric acid and an amine. This chemical has been used as a reagent for introducing amines into organic compounds. 5-Amino-1,2,3-anilidothiobiazole can be recycled and reused due to its low cost and high reactivity. It can also be used to synthesize other chemicals such as 2-(trimethylsilyl)ethanol. The chemical reacts with thionyl chloride in acetonitrile to produce chlorinated products such as chloroacetic acid or chloromethyl methyl ether. If the reaction is conducted in an inorganic solvent such as water, it will produce hydrogen fluoride gas or hydrochloric acid gas. This chemical also undergoes carbonylation reactions with phenols or nitrobenzene in the presence