CAS 412950-08-4: Rilapladib
Formula:C40H38F5N3O3S
InChI:InChI=1S/C40H38F5N3O3S/c1-51-22-21-46-19-17-32(18-20-46)47(24-27-9-11-28(12-10-27)29-13-15-31(16-14-29)40(43,44)45)37(50)25-48-35-8-3-2-6-33(35)36(49)23-38(48)52-26-30-5-4-7-34(41)39(30)42/h2-16,23,32H,17-22,24-26H2,1H3
InChI key:InChIKey=NNBGCSGCRSCFEA-UHFFFAOYSA-N
SMILES:C(C(N(CC1=CC=C(C=C1)C2=CC=C(C(F)(F)F)C=C2)C3CCN(CCOC)CC3)=O)N4C=5C(C(=O)C=C4SCC6=C(F)C(F)=CC=C6)=CC=CC5
Synonyms:- 1(4H)-Quinolineacetamide, 2-[[(2,3-difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4′-(trifluoromethyl)[1,1′-biphenyl]-4-yl]methyl]-
- 2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide
- N-[1-(2-Methoxyethyl)piperidin-4-yl]-2-[2-[(2,3-difluorobenzyl)thio]-4-oxo-4H-quinolin-1-yl]-N-[(4′-trifluoromethylbiphenyl-4-yl)methyl]acetamide
- Sb 659032
- Rilapladib
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Found 3 products.
Rilapladib
CAS:Rilapladib is an inhibitor of the class of lipoprotein-associated phospholipase A2 (LpPLA2) that has a potent inhibitory effect on the synthesis of pro-inflammatory and pro-thrombotic mediators. Rilapladib is a lipid-lowering drug that inhibits LpPLA2, which is involved in the production of inflammatory and thrombotic mediators. The clinical efficacy and safety of rilapladib has been studied in patients with coronary artery disease who are at risk for cardiovascular events. Results from these studies reveal that rilapladib can reduce the risk of cardiovascular events.Formula:C40H38F5N3O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:735.81 g/molRilapladib
CAS:Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activatingFormula:C40H38F5N3O3SPurity:97.29%Color and Shape:SolidMolecular weight:735.8Ref: TM-T16751
1mg93.00€5mg227.00€10mg369.00€25mg622.00€50mg885.00€100mg1,206.00€1mL*10mM (DMSO)369.00€
