CAS 41526-21-0: N-[4-Bromo-2-(2-pyridinylcarbonyl)phenyl]-2-chloroacetamide

Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide-d4 is the isotope labelle danalog of N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide. N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500). References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)

Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500). References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)

2-(2-Chloroacetamido-5-bromobenzoyl)pyridine is a small molecule that has been studied for its potential use as an anti-cancer agent. This compound binds to the active site of DNA polymerase, inhibiting its function and disrupting DNA synthesis. 2-(2-Chloroacetamido-5-bromobenzoyl)pyridine has a hydrogen bond with the carbonyl group on the benzoyl group in the crystal structure. The crystallographic data shows that this compound has dimers and orthorhombic crystals. 2-(2-Chloroacetamido-5-bromobenzoyl)pyridine also forms intermolecular hydrogen bonds with other molecules of the same kind.