CAS 4165-61-1: Benzen-2,3,4,5,6-d5-amine

Aniline-2',3',4',5',6'-D5 >98 Atom % D 5ml ampoule

Aniline-2',3',4',5',6'-D5 >98 Atom % D 1ml ampoule

Stability Air Sensitive, Material darkens in storage with no loss in purity Applications Isotope labelled Aniline (A662475), which is used in the manufacture of dyes, medicinals, resins, varnishes, perfumes, as a vulcanizing rubber or even as a solvent (1,2). Hazardous and noxious substance which affects the early life stages of marine animals (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Dyes and metabolites, Environmental Testing Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References 1. Cunha, I. et. al.: Environ. Sci. Pollut. Res. Int. 2017 Mar 10.2. Zhang, X. et al.: Synthesis. 2013 45(10): 1357-13633. Barkov, A. et al.: Russ. Chem. Bull. 2012. Aug:61(8) pp1564-9

Aniline D5 is a metabolic probe used to study the activation of carcinogens. Aniline D5 inhibits the growth of cancer cells by binding to amines, which are present in epidermal growth factor and other growth factors. When an anhydrous sodium hydrogen bond forms between the amines and the aniline, it causes a frequency shift in the aromatic ring that leads to a change in its physical properties. This change can be detected using high-resolution NMR spectroscopy. The sensitivity of this technique has been improved by adding activated charcoal as a matrix effect.

Aniline-d5 is a deuterated isotope marker of Aniline, which can be used for isotope tracing.Aniline induces toxicity to the spleen through iron overload.