CAS: 42123-27-3

Applications Tetradehydropodophyllotoxin is a aryl-naphthalene lignans that was shown to exhibit anticancer activities. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Hui, J., et al.: Med. Chem. Res., 21, 3994 (2012); Tian, H., et al.: Brit. J. Pharmacol., 150, 321 (2007); Ter, Harr, E., et al.: Bioorg. Med. Chem., 4, 1659 (1996);

Tetradehydropodophyllotoxin

Dehydropodophyllotoxin is a lignan compound, which is derived from the roots and rhizomes of the plant genus Podophyllum. It exhibits its activity primarily as an inhibitor of microtubule assembly. Microtubules are essential components of the cell cytoskeleton, playing a critical role in cell division and intracellular transport. By interfering with microtubule dynamics, dehydropodophyllotoxin disrupts mitosis, leading to cell cycle arrest and potential apoptosis in rapidly dividing cancer cells. This compound has garnered interest in the field of oncology due to its potential antitumor properties. Researchers are exploring its application in the development of chemotherapeutic agents aimed at various types of cancer. Although its precise molecular mechanisms are still under investigation, the ability of dehydropodophyllotoxin to inhibit microtubule formation represents a promising avenue for cancer treatment strategies. Scientists continue to study its pharmacokinetics and therapeutic efficacy in order to better understand its role and optimize its application in clinical settings.

Tetradehydropodophyllotoxin (Dehydropodophyllotoxin) has anti-tumor activity.