CAS: 423748-02-1

MS37452 is an antimicrobial peptide, which is a type of biomolecule sourced from natural or synthetic origins. These peptides are known for their ability to interact with bacterial cell membranes through electrostatic interactions and hydrophobic insertions. This mode of action leads to the disruption of bacterial cell integrity, resulting in cell lysis and death. In scientific contexts, MS37452 is utilized primarily for its potent antibacterial properties, making it a valuable tool in research exploring new antibiotics or studying microbial resistance mechanisms. Its application spans microbiological assays, where it aids in evaluating the effectiveness of novel antibiotic formulations or in the development of anti-infective materials. The unique mechanism by which MS37452 operates provides insight into overcoming antibiotic resistance, a pressing concern in contemporary medicine. Its incorporation into studies on microbial pathogenesis further illustrates its diverse utility in scientific investigations.

MS37452

MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).