CAS 4241-27-4: 1,2-Dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile

3-Cyano-6-methyl-2-(1H)-pyridinone is a supermolecule that spontaneously forms in the absence of any template. It has been shown to have anti-bacterial activity against many Gram-positive bacteria. 3-Cyano-6-methyl-2-(1H)-pyridinone inhibits the formation of benzothiadiazole, which is an intermediate in the synthesis of phenazine. The compound has been shown to inhibit benzothiadiazole pathways in bacterial cells and also inhibits the formation of beta sheets, which are important for architecture, coordination and orientation. 3-Cyano-6-methyl-2-(1H)-pyridinone has a square planar structure and can form multidimensional architectures when coordinated with metals such as copper, zinc and nickel.

3-Cyano-6-methyl-2(1H)-pyridinone is a reactant used in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. 3-It has also been used in the preparation of the N3-pyridyl thiamine, a potent in vitro thiamine antagonist. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile