CAS 425637-18-9: Sotrastaurin
Formula:C25H22N6O2
InChI:InChI=1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,29,32,33)
InChI key:InChIKey=OAVGBZOFDPFGPJ-UHFFFAOYSA-N
SMILES:O=C1C(=C(C(=O)N1)C=2C=3C(NC2)=CC=CC3)C=4C5=C(N=C(N4)N6CCN(C)CC6)C=CC=C5
Synonyms:- 1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[2-(4-methyl-1-piperazinyl)-4-quinazolinyl]-
- 3-(1H-Indol-3-yl)-4-[2-(4-methyl-1-piperazinyl)-4-quinazolinyl]-1H-pyrrole-2,5-dione
- 3-(1H-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione
- Sotrastaurin
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Found 7 products.
3-(1H-Indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)-1H-pyrrole-2,5-dione
CAS:Purity:98.0%Molecular weight:438.4909973144531Ref: 10-F547222
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquireSotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48Ref: TM-T6278
1mg49.00€5mg96.00€10mg166.00€25mg313.00€50mg553.00€100mg790.00€500mg1,578.00€1mL*10mM (DMSO)115.00€Sotrastaurin
CAS:Sotrastaurin is a drug that inhibits protein kinase, which are enzymes that catalyze the transfer of phosphate groups in proteins. It blocks the IL-2 receptor and its associated signaling pathways, which leads to an inhibition of T cell proliferation. Sotrastaurin has also been shown to be effective against bowel disease in animal models. The drug may reduce the levels of α1-acid glycoprotein and inhibit the polymerase chain reaction (PCR). It prevents oxidative injury by suppressing IL-2 receptor-associated protein tyrosine kinases. This drug also decreases α1-acid glycoprotein levels, which are elevated in people with bowel disease.Formula:C25H22N6O2Purity:Min. 95%Molecular weight:438.48 g/mol3-(1H-Indol-3-Yl)-4-(2-(4-Methylpiperazin-1-Yl)Quinazolin-4-Yl)-1H-Pyrrole-2,5-Dione
CAS:3-(1H-Indol-3-Yl)-4-(2-(4-Methylpiperazin-1-Yl)Quinazolin-4-Yl)-1H-Pyrrole-2,5-DioneMolecular weight:438.48g/mol
