CAS 426-15-3: 21-Deoxydexamethasone
Formula:C22H29FO4
InChI:InChI=1S/C22H29FO4/c1-12-9-17-16-6-5-14-10-15(25)7-8-19(14,3)21(16,23)18(26)11-20(17,4)22(12,27)13(2)24/h7-8,10,12,16-18,26-27H,5-6,9,11H2,1-4H3/t12-,16+,17+,18+,19+,20+,21+,22+/m1/s1
InChI key:InChIKey=IKGBPSZWCRRUQS-QAHQDLQKSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(C)=O)(O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:- (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
- 9-Fluoro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-16α-methyl-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-
- 21-Deoxydexamethasone
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Found 5 products.
(11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione21-Deoxydexamethasone
CAS:Controlled ProductFormula:C22H29FO4Color and Shape:NeatMolecular weight:376.462Dexamethasone Impurity 1
CAS:Formula:C22H29FO4Color and Shape:White To Off-White SolidMolecular weight:376.4721-Deoxydexamethasone
CAS:21-Deoxydexamethasone is a synthetic corticosteroid that has been extracted from the adrenal cortex of animals. It is hydrolysed to deoxycorticosterone, which is then converted to corticosterone in the liver. The 21-deoxysteroid and its derivatives are used as a source of cortisone, while the 21-hydroxylated compounds are used in some synthetic glucocorticoids. Deoxycorticosterone can also be converted into hydrocortisone by β-glucuronidase. It has been shown that this drug has a high urinary excretion rate (approximately 50%), and has been analysed using spectrometry to identify conjugates. Chemical ionisation was used for identification of metabolites in urine samples, with detection limits of 0.1 ng/mL for metabolites such as 17α-dehydrodeoxycortisol and 17α-hydroxydeoxycortisolFormula:C22H29FO4Purity:Min. 95%Molecular weight:376.5 g/mol
