Pyrimidine-4-carbonitrile is a heterocyclic organic compound characterized by a pyrimidine ring with a cyano group (-C≡N) attached at the 4-position. This compound features a six-membered aromatic ring containing two nitrogen atoms at the 1 and 3 positions, which contributes to its basicity and reactivity. Pyrimidine-4-carbonitrile is typically a colorless to pale yellow solid and is soluble in polar organic solvents. It is known for its applications in pharmaceuticals and agrochemicals, serving as a building block in the synthesis of various biologically active compounds. The presence of the cyano group enhances its reactivity, making it useful in nucleophilic substitution reactions and other synthetic pathways. Additionally, pyrimidine derivatives are often studied for their potential as antiviral, anticancer, and anti-inflammatory agents. Safety data indicates that, like many nitriles, it should be handled with care due to potential toxicity and irritant properties. Overall, pyrimidine-4-carbonitrile is a versatile compound with significant importance in organic synthesis and medicinal chemistry.

Pyrimidine-4-carbonitrile

4-Cyanopyrimidine

Pyrimidine-4-carbonitrile is a drug substance that is used in the preparation of serotonin, amide, and carboxamidoxime. It is also an active methylene with a n-oxide, peroxide, and active hydrogen. The pharmacokinetic properties of pyrimidine-4-carbonitrile are not well understood due to its low solubility in water. Pyrimidine-4-carbonitrile has been shown to react with nucleophiles such as amines and sulfoxides. This substance can also form an unstable sulfoxide or aldehyde when heated even at room temperature.

CAS 42839-04-3: Pyrimidine-4-carbonitrile

4-Cyanopyrimidine

Ref: 10-F076408

Pyrimidine-4-carbonitrile

Ref: IN-DA003L9N

Pyrimidine-4-carbonitrile

Ref: 3D-FP144184

Pyrimidine-4-carbonitrile

Ref: 54-OR015037