2-Chloro-4-ethoxyquinoline is an organic compound characterized by its quinoline structure, which consists of a fused benzene and pyridine ring. The presence of a chlorine atom at the second position and an ethoxy group at the fourth position of the quinoline ring significantly influences its chemical properties and reactivity. This compound typically appears as a yellow to brown solid and is sparingly soluble in water but more soluble in organic solvents such as ethanol and dichloromethane. It may exhibit biological activity, making it of interest in medicinal chemistry and pharmacology. The chlorine substituent can enhance the compound's lipophilicity, potentially affecting its interaction with biological targets. Additionally, 2-chloro-4-ethoxyquinoline can undergo various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions, due to the presence of the reactive functional groups. Safety data should be consulted for handling and storage, as with many halogenated compounds, it may pose health risks if not managed properly.

2-chloro-4-ethoxyquinoline

4295-08-3: Quinoline, 2-Chloro-4-Ethoxy-, 2-Chloro-4-ethoxyquinoline

2-Chloro-4-ethoxyquinoline

Applications Quinoline derivative used in the preparation of compounds with anticonvulsant activity as well as compounds with potent antibacterial activity against gram-positive pathogens.
References Guo, L. et al.: Eur. J. Med. Chem., 44, 954 (2009); Jarvest, R.L. et al.: J. Med. Chem., 45, 1959 (2002);


CAS 4295-08-3: 2-chloro-4-ethoxyquinoline

2-Chloro-4-ethoxyquinoline

Ref: 3D-EAA29508

2-Chloro-4-ethoxyquinoline

Ref: TR-C365730

2-CHLORO-4-ETHOXYQUINOLINE

Ref: IN-DA00C9XM