DL-Cyclobutylalanine is a non-proteinogenic amino acid characterized by its cyclobutane ring structure attached to the alanine backbone. This compound is an isomer of cyclobutylalanine, which means it exists in both D- and L- forms, contributing to its classification as a racemic mixture. The presence of the cyclobutane ring introduces unique steric and electronic properties, potentially influencing its interactions in biological systems. DL-Cyclobutylalanine is of interest in medicinal chemistry and peptide synthesis due to its ability to modify peptide conformation and stability. The compound is typically white to off-white in appearance and is soluble in polar solvents. Its applications may extend to research in drug design, where the incorporation of non-standard amino acids can enhance the pharmacological properties of peptides. As with many amino acids, the study of DL-Cyclobutylalanine can provide insights into protein folding, enzyme activity, and receptor binding, making it a valuable subject in biochemical research.

DL-Cyclobutylalanine

4426-06-6: 2-Amino-3-Cyclobutylpropanoic Acid, DL-2-Amino-3-cyclobutyl-propionsaeure, 3-Cyclobutylalanine

3-Cyclobutylalanine is a potent inhibitor of the enzyme dihydroorotase that catalyzes the conversion of 3-hydroxy-L-tyrosine to L-3,4-dihydroxyphenylalanine. This compound has been shown to inhibit the production of deregulated peptides and linear molecules that are synthetized by mutant aspartate aminotransferases (e.g., G551D). 3-Cyclobutylalanine was also found to be an effective inhibitor against E. coli and other bacteria in the nanomolar range.

CAS 4426-06-6: DL-Cyclobutylalanine

3-Cyclobutylalanine

Ref: 3D-EAA42606

DL-Cyclobutylalanine

Ref: IN-DA00DBAI

2-Amino-3-cyclobutylpropanoic acid

Ref: 10-F232354

3-Cyclobutylalanine

Ref: 54-OR451069