CAS 4443-09-8: Norwogonin

Norwogonin

Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).

5,7,8-Trihydroxyflavone is a flavonoid compound, which is a type of phytochemical derived from the structural class of polyphenols commonly found in various plants. This specific flavonoid is naturally occurring in certain botanicals and can be isolated through extraction processes. The mode of action of 5,7,8-Trihydroxyflavone involves its interaction with cellular pathways, primarily acting as an antioxidant. It mitigates oxidative stress by scavenging free radicals and upregulating the expression of antioxidant enzymes. In terms of applications, 5,7,8-Trihydroxyflavone is of significant interest in the field of neuroscience due to its potential neuroprotective properties. Research suggests that it may influence neurotrophic signaling pathways, enhancing neuronal survival and function. Additionally, its antioxidative capabilities are being explored for therapeutic benefits in conditions characterized by oxidative damage and neurodegeneration. Researchers are particularly focused on its implications in aging and age-related neurological disorders, considering its ability to modulate cellular processes related to oxidative damage and neuronal health. Potential applications extend to pharmacological interventions aimed at preventing or mitigating neurodegenerative diseases.