4-Amino-3-(trifluoromethyl)phenol, with the CAS number 445-04-5, is an organic compound characterized by the presence of an amino group (-NH2) and a trifluoromethyl group (-CF3) attached to a phenolic ring. This compound typically appears as a solid and is known for its potential applications in various fields, including pharmaceuticals and agrochemicals. The trifluoromethyl group enhances the compound's lipophilicity and metabolic stability, making it of interest in drug design. The amino group contributes to its reactivity, allowing for further chemical modifications. Additionally, 4-amino-3-(trifluoromethyl)phenol exhibits properties such as solubility in polar solvents and may participate in hydrogen bonding due to the hydroxyl group (-OH) inherent in phenols. Its unique structure and functional groups can influence its biological activity and interactions with other chemical entities, making it a subject of study in medicinal chemistry and material science. Safety data should be consulted for handling and usage, as with any chemical substance.

4-amino-3-(trifluoromethyl)phenol

445-04-5: Phenol, 4-Amino-3-(Trifluoromethyl)-

4-Amino-3-(trifluoromethyl)phenol

4-Amino-3-(trifluoromethyl)phenol is a phenolic compound that is used as an herbicide. It inhibits estrogen synthesis by binding to the estrogen receptor and preventing the formation of 2,5-dihydroxybenzoic acid from 4-hydroxyphenylpyruvic acid. The incubated constant for this reaction was found to be 1.7 μM. The glucuronide conjugate of 4-amino-3-(trifluoromethyl)phenol is eliminated in the urine, which may account for its low toxicity in humans. This compound has been shown to have agonist activities on MCF-7 cells, which are human breast cancer cells. A liquid chromatography tandem mass spectrometry (LC/MS/MS) method was used to measure the concentration of 4-amino-3-(trifluoromethyl)phenol in samples of human urine and

CAS 445-04-5: 4-amino-3-(trifluoromethyl)phenol

4-Amino-3-(trifluoromethyl)phenol

Ref: 10-F237398

4-amino-3-(trifluoromethyl)phenol

Ref: 3D-FA104996

2-Amino-5-hydroxybenzotrifluoride

Ref: 54-PC6048

Phenol, 4-amino-3-(trifluoromethyl)-

Ref: IN-DA00I8FN