1,3-Dithiolan-2-imine is a heterocyclic compound characterized by a five-membered ring containing two sulfur atoms and an imine functional group. Its molecular structure features a dithiolane ring, which contributes to its unique chemical properties. The presence of the imine group (C=N) indicates that it can participate in various chemical reactions, including nucleophilic additions and condensation reactions. This compound is typically colorless to pale yellow and may exhibit a distinct odor. It is soluble in polar organic solvents, which enhances its utility in organic synthesis and as a potential intermediate in the preparation of more complex molecules. The dithiolan ring structure can also impart stability and reactivity, making it of interest in materials science and medicinal chemistry. Additionally, 1,3-Dithiolan-2-imine may exhibit biological activity, although specific applications and effects would depend on further research and context. Safety data should be consulted for handling and storage, as with any chemical substance.

1,3-Dithiolan-2-imine

4472-81-5: Imidocarbonicacid, dithio-, cyclic ethylene ester (6CI,8CI), 1,2-Ethanedithiol, cyclicdithioimidocarbonate, 1,2-Ethanedithiol, cyclic ester with dithioimidocarbonicacid, Carbonimidodithioic acid, cyclic 1,2-ethanediyl ester

Applications 1,3-Dithiolan-2-imine is one of the metabolites of Cyolane, a systemic organophosphate insecticide that is effective in larvae of all stages and is also persistent for a long period of time. Cyolane is toxic and also known to cause an asthmatic inflammatory reaction in the lungs of juvenile rats.
References Bahig, M. & Wafa, D.: Isot. Rad. Res., 13, 153 (1981); Mistric, J. & Pittard, W.: J. Econ. Entomol., 66, 232 (1973); Pasarela, N. & Orloski, E.: Anal. Method. Pestic. Plant Growth Reg., No vol. given, No pp. given (1973)


Dithiolan-2-imine (DTTI) is a regiospecific chemical reagent that is used in organic synthesis. It reacts with thiourea to produce dithiolanes and dithiane derivatives, which are important in the preparation of many pharmaceuticals. DTTI also reacts with collagen to form a ligand that binds to the active sites on the surface of cancer cells. This binding inhibits the growth and proliferation of cancer cells by preventing cell division. DTTI can be used as an antibiotic agent against bacteria such as Pseudomonas aeruginosa, which is a common cause of hospital-acquired infections. DTTI has been shown to have anti-inflammatory properties, such as its ability to inhibit prostaglandin synthesis.

CAS 4472-81-5: 1,3-Dithiolan-2-imine

1,3-Dithiolan-2-imine

Ref: TR-D494695

Dithiolan-2-imine

Ref: 3D-FD41227