
CAS 448906-42-1: 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester
Formula:C14H10N2O3S
InChI:InChI=1S/C14H10N2O3S/c1-19-14(18)11-7-20-13(16-11)12(17)9-6-15-10-5-3-2-4-8(9)10/h2-7,15H,1H3
InChI key:InChIKey=KDDXOGDIPZSCTM-UHFFFAOYSA-N
SMILES:C(=O)(C=1C=2C(NC1)=CC=CC2)C3=NC(C(OC)=O)=CS3
Synonyms:- 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester
- 2-(1′H-Indole-3′-carbonyl)thiazole-4-carboxylic acid methyl ester
- 4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester
- Ari-001
- Methyl 2-(1H-indol-3-ylcarbonyl)-1,3-thiazole-4-carboxylate
- ITE
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Found 6 products.
ITE
CAS:ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.Formula:C14H10N2O3SPurity:97.91%Color and Shape:SolidMolecular weight:286.31ITE
CAS:Endogenous non-toxic agonist of the aryl hydrocarbon receptor (AhR) with immunosuppressive activity. The compound also inhibits the nuclear translocation of Smad2/3/4 leading to aberrant Transforming Growth Factor-β1 (TGFβ1) signaling. It inhibits myofibroblast differentiation and is a potential anti-scarring agent.Formula:C14H10N2O3SPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:286.31 g/molITE
CAS:Formula:C14H10N2O3SPurity:>95.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:286.31ITE - Bio-X ™
CAS:This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C14H10N2O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:286.31 g/molITE
CAS:Controlled ProductApplications ITE is an endogenous AHR ligand that parenterally or orally induces FoxP3+ Treg that suppress exprimental autoimmune encephalomyelitis. ITE promotes the induction of active immunology tolerance and identifies nontoxic endogenous AHR ligands. References Quintana, F., et al.: Proc. Natl. Acad. Sci. USA, 107, 20768 (2010);Formula:C14H10N2O3SColor and Shape:NeatMolecular weight:286.31