CAS 4507-84-0: 3-nitronaphthalene-1-carboxylic acid

3-Nitro-1-naphthoicacid is an inhibitor of protein kinase C (PKC) that binds to the hydrophobic pocket in PKC. It has been shown to inhibit PKC, which plays a role in various cellular processes including cell proliferation, differentiation, and apoptosis. The inhibition of PKC leads to a decrease in the activity of cyclin D1 and cyclin E, which are important for the G2-M transition. 3-Nitro-1-naphthoicacid also inhibits kallikrein, an enzyme that is involved in the activation of bradykinin and is essential for blood coagulation. 3-Nitro-1-naphthoicacid has been found to be a potent fluorescent probe with fluorescence resonance energy transfer (FRET) properties.