1,3-Difluoro-2-propanone, with the CAS number 453-14-5, is a fluorinated ketone characterized by the presence of two fluorine atoms and a ketone functional group within a three-carbon chain. This compound typically appears as a colorless liquid with a distinctive odor. It is known for its reactivity due to the electronegative fluorine atoms, which can influence its chemical behavior and interactions. The presence of the ketone group makes it a potential candidate for various organic synthesis reactions, including nucleophilic additions. 1,3-Difluoro-2-propanone is soluble in organic solvents and may exhibit moderate volatility. Its physical and chemical properties, such as boiling point and density, can vary based on environmental conditions. As with many fluorinated compounds, it may have specific applications in pharmaceuticals, agrochemicals, or as an intermediate in organic synthesis. However, safety precautions should be taken when handling this substance due to potential toxicity and environmental impact.

1,3-Difluoro-2-propanone

453-14-5: 2-Propanone,1,3-difluoro-, sym-Difluoroacetone, NSC 21301, 1,3-Difluoroacetone, 2-Propanone, 1,3-difluoro-, 1,3-Difluoro-2-propanone

1,3-Difluoroacetone is a chemical compound that is used for biological studies. It has been shown to have protease activity in biological samples. 1,3-Difluoroacetone has been studied for its potential as an anti-cancer drug and has also been shown to have toxic effects on prostate cancer cells. It has also been found to induce pluripotent stem cells from human fibroblasts and hl-60 cells (a leukemia cell line). The mechanism of action of 1,3-difluoroacetone is not well understood but it seems to be irreversible inhibition of mitochondrial membrane potential.

1,3-Difluoroacetone

1,3-Difluoroacetone is used as pharmaceutical intermediate and for chemical research. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

CAS 453-14-5: 1,3-Difluoro-2-propanone

1,3-Difluoroacetone

Ref: 3D-FD77260

1,3-Difluoroacetone

Ref: 54-PC066

1,3-Difluoroacetone, 98%

Ref: 02-H51145