CAS 4549-32-0: 1,8-Dibromooctane

Applications 1,8-Dibromooctane is used as a reagent in the synthesis of novel 7-aminoalkyl-substituted flavonoid derivatives as potential cholinesterase inhibitors. References Luo, W., et al.: Bioorg. Med. Chem., 24, 672 (2016)

Acyclic nucleoside phosphonates are a class of compounds that have been shown to inhibit the replication of human immunodeficiency virus (HIV) and other viruses. 1,8-Dibromooctane is a compound in this class and has been shown to enhance the transfection efficiency of DNA into mammalian cells. This molecule can also inhibit HIV from binding to the CD4 receptor by competing with it for binding sites on the surface of the cell. 1,8-Dibromooctane has a molecular weight of 242.16 g/mol and optical properties that are characteristic of an aliphatic compound. It also does not dissolve in water, but does dissolve in sodium sulfide and ethyl group.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1,8-Dibromooctane

1,8-Dibromooctane is used as an additive in the preparation poly[[4,8-bis[(2-ethylhexyl)oxy]benzo[1,2-b:4,5-b']dithiophene-2,6-diyl][3-fluoro-2-[(2-ethylhexyl)carbonyl]thieno[3,4-b]thiophenediyl]]:[6,6]-phenylC71-butyric acid methyl ester, which finds application in the fabrication of organic photovoltaics (OPVs). Further, it is used in the preparation of (1,4-bis-(8-bromooctyloxy)-benzene). This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.