CAS 4606-07-9: Ethyl cyclopropanecarboxylate

Ethyl cyclopropanecarboxylate is a reagent used in the addition of cyclopropane. It acts as annulation reagent for the conversion of aromatics to 2-methylindanones under Friedel-Crafts conditions. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ethyl cyclopropanecarboxylate

Applications Reagent used in the addition of cyclopropane. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Cave, C., et al.: Eur. J. Med. Chem., 25, 75 (1990), Kiyama, R., et al.: Chem. Pharm. Bull., 43, 960 (1995), Humphries, P., et al.: Bioorg. Med. Chem. Lett., 16, 6120 (2006),

Ethyl cyclopropylcarboxylate is a synthetic drug that is used in the treatment of chronic bronchitis, hepatitis, and autoimmune diseases. It has been shown to inhibit the activity of ns3 protease, an enzyme that plays a role in the synthesis of pro-inflammatory cytokines. Ethyl cyclopropylcarboxylate is also used as a solvent for organic compounds, such as pharmaceutical preparations and wastewater treatment. The compound has been shown to have cancer-fighting properties and can be used for the preparation of samples for chromatography or mass spectrometry. Ethyl cyclopropylcarboxylate is also an inhibitor of carboxylesterases, which are enzymes that cleave esters from carboxylic acids. This inhibition leads to increased levels of carboxylic acids and metabolites in urine, which can be detected by gas chromatography-mass spectrometry (GC-MS).