CAS 461432-26-8: Dapagliflozin
Formula:C21H25ClO6
InChI:InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1
InChI key:InChIKey=JVHXJTBJCFBINQ-ADAARDCZSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2
Synonyms:- (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-<span class="text-smallcaps">D</span>-glucitol
- (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
- (1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol
- <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-
- Bms-512148
- D-Glucitol, 1,5-Anhydro-1-C-[4-Chloro-3-[(4-Ethoxyphenyl)Methyl]Phenyl]-, (1S)-
- Dapagliflozin
- Dapagliflozin free base
- (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
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Found 17 products.
Dapagliflozin
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C21H25ClO6Color and Shape:Crystalline powder, White to light yellowMolecular weight:408.88(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
CAS:Formula:C21H25ClO6Purity:97%Color and Shape:SolidMolecular weight:408.8726Ref: IN-DA0039GJ
1g129.00€5g255.00€10g628.00€25gTo inquire100gTo inquire10mg29.00€50mg30.00€100mg52.00€250mg61.00€Dapagliflozin
CAS:Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formula:C21H25ClO6Purity:99.5% - 99.74%Color and Shape:SolidMolecular weight:408.87Ref: 10-F794039
1gTo inquire5gTo inquire10gTo inquire25gTo inquire100gTo inquire10mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquireDapagliflozin
CAS:Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. SGLT2 is located in the proximal convoluted tubule and when it is inhibited the reabsorption of glucose into the kidneys is prevented and instead glucose is excreted in the urine. As a result glucose levels are reduced. Dapagliflozin is metabolized into to its inactive metabolite 3-O-glucuronide by the UGT1A9 enzyme present in the liver and the kidneys. In addition, dapagliflozin has been shown to cause weight loss and decrease the risk of cardiovascular events such as congestive heart failure.Formula:C21H25ClO6Purity:Min. 98 Area-%Color and Shape:White Yellow PowderMolecular weight:408.87 g/molDapagliflozin
CAS:Stability Hygroscopic Applications A sodium-glucose transporter 2 inhibitor. References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)Formula:C21H25ClO6Color and Shape:White To Light YellowMolecular weight:408.87Dapagliflozin
CAS:Formula:C21H25ClO6Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:408.88Dapagliflozin
CAS:Formula:C21H25ClO6Purity:≥ 98.0% (dried basis)Color and Shape:White to light-yellow powderMolecular weight:408.87Dapagliflozin - Bio-X ™
CAS:Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. It inhibits glucose reabsorption in the proximal tubule of the nephron and results in glycosuria, which helps to improve glycaemic control. Also, Dapagliflozin is used to lower the risk of sustained eGFR decline, end-stage renal disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease who are at risk of progression. Dapagliflozin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C21H25ClO6Purity:Min. 99 Area-%Color and Shape:PowderMolecular weight:408.87 g/mol
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