4-Quinolinamine, N-hydroxy-, 1-oxide, also known by its CAS number 4637-56-3, is a chemical compound characterized by its quinoline structure, which is a bicyclic aromatic compound containing a nitrogen atom in the ring. This substance features a hydroxylamine functional group, which contributes to its reactivity and potential applications in various chemical processes. It is typically a solid at room temperature and may exhibit solubility in polar solvents due to the presence of the hydroxylamine group. The compound is of interest in medicinal chemistry and may have implications in the development of pharmaceuticals, particularly due to its potential biological activity. Additionally, its oxidation state can influence its reactivity, making it a subject of study in organic synthesis and material science. Safety data should be consulted for handling and usage, as compounds with similar structures can exhibit varying degrees of toxicity and environmental impact.

4-Quinolinamine, N-hydroxy-, 1-oxide

4637-56-3: (4E)-1-hydroxyquinolin-4(1H)-one oxime, (4Z)-1-hydroxyquinolin-4(1H)-one oxime, 4-(Hydroxyamino)quinoline 1-oxide, 4-Hydroxyaminoquinoline N-oxide, 4-Hydroxylaminoquinoline 1-oxide, 4-Hydroxylaminoquinoline N-oxide, 4-Quinolinamine, N-hydroxy-, 1-oxide, N-hydroxyquinolin-4-amine 1-oxide, NSC 177384, Quinoline, 4-(hydroxyamino)-, 1-oxide

4-Aminoquinoline N-oxide (4AQNO) is a reactive oxygen species that has been shown to cause cancer in animal studies. 4AQNO is found in the skin cells of patients with cancer, and its reaction mechanism is thought to be similar to that of other reactive oxygen species. The chemical substance 4AQNO reacts with DNA at the level of the pyrimidine bases (cytosine, thymine, and uracil) and causes oxidative damage. This process leads to the formation of 8-hydroxydeoxyguanosine (8OHdG), which can be used as a marker for oxidative damage. Type strain bacteria are more sensitive than wild-type strains to 4AQNO because they lack protective enzymes such as n-oxide reductase. In addition, carcinogenesis is associated with mutations in genes encoding redox potential markers.

CAS 4637-56-3: 4-Quinolinamine, N-hydroxy-, 1-oxide

4-(Hydroxyamino)quinoline N-Oxide

Ref: 3D-FH75589

4-(Hydroxyamino)quinoline N-Oxide

Ref: 3B-H0515

4-(HYDROXYAMINO)QUINOLINE N-OXIDE

Ref: IN-DA003K8H