CAS 464-45-9: (-)-Borneol

(-)-borneol (L-Borneol) has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.

(-)-Borneol is a monoterpenoid that is found in plants such as Angelica Dahurica, Salvia Miltiorrhiza, and Rhizoma Gastrodiae. (-)-Borneol has been shown to inhibit the activity of complex enzymes such as fructosyltransferase, which is involved in the synthesis of fructose-1,6-bisphosphate. This compound also displays significant cytotoxicity against cancer cells and induces apoptosis by inhibiting DNA binding activity. (-)-Borneol also has anti-inflammatory properties and can be used for the treatment of inflammatory diseases such as asthma. It inhibits prostaglandin synthesis by blocking cyclooxygenases (COX). Experimental studies have shown that borneol can inhibit the growth of Mycobacterium tuberculosis and Mycobacterium avium complex.

(-)-Borneol is used to prepare its esters by reacting with acids. Its derivatives are used as chiral ligands in asymmetric synthesis. It is also used in flavors and perfumes. Further, it is used in traditional Chinese medicine as moxa. In addition to this, it is used as a component of many essential oils and also used as a natural insect repellent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Cyclic alcohol

(-)-borneol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

(-)-Borneol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Applications (-)-Borneol, is used in traditional Chinese medicine as moxa. It is a component of many essential oils, and can be also used as natural insect repellent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lide, D. R., et al.: Flav. Frag. J., 7, 263 (2006); Wu, H., et al.: Yaowu Fenxi Zazhi, 30, 1941 (2010);