CAS 4664-00-0: 5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione

5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione

Quinolinimide is a terpene with a fatty acid side chain and an anilino group. It is synthesized from choline by pyridoxal phosphate-dependent enzyme, quinolinic acid synthetase. Quinolinimide has been shown to be active against the Na+ channel in nerve cells, which is responsible for the passage of ions across the membrane. This results in depolarization of the nerve cell and an increase in acetylcholine release. Quinolinimide blocks the Na+ channel by binding to the terminal residues on its outer surface, which prevents ion flow across the membrane and leads to paralysis.