CAS 467-81-2: (22β)-22-[[(2Z)-2-Methyl-1-oxo-2-buten-1-yl]oxy]-3-oxoolean-12-en-28-oic acid

Lantadene A is a pentacyclic triterpenoid, which is a natural compound extracted from the leaves of the Lantana camara plant. This compound is primarily known for its hepatotoxic properties, which occur through inhibition of liver mitochondrial functions, affecting cellular energy production and leading to cell damage. This mode of action is particularly relevant in the study of plant-induced liver toxicity. In scientific research, Lantadene A is utilized to investigate the biochemical pathways of hepatotoxicity and to develop potential antidotes and protective measures against such plant toxins. Additionally, due to its defined structure and mode of action, it serves as an important model compound for the study of similar triterpenoids. Understanding the impact of Lantadene A also aids in evaluating the ecological and agricultural consequences of Lantana camara proliferation, notably its effects on grazing animals. This underscores its significance in pharmacological and toxicological research, as it helps delineate the mechanisms of plant-derived toxicity and informs the management of invasive plant species.

Rehmannic acid and oleanolic acetate inhibit succinoxidase activity.