CAS 471-05-6: Zerumbone

Applications Zerumbone can be used in biological use and study of research progress on the natural product induced DNA damage response in cancer cells. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Ren, G., et al.: Zhongguo Zhongyao Zazhi, 40, 4797 (2015)

zerumbone

Zerumbone is a naturally occurring sesquiterpene, which is primarily extracted from the rhizomes of Zingiber zerumbet, a species of wild ginger. As a phytochemical, it has garnered attention for its intriguing mode of action at the molecular level, involving the modulation of cellular signaling pathways. Zerumbone is known to interact with multiple targets, potentially through its reactive α,β-unsaturated carbonyl group, allowing it to form covalent bonds with nucleophilic sites on proteins. This interaction is crucial for its role in altering regulatory proteins involved in inflammation, apoptosis, and anti-neoplastic activities. The uses and applications of Zerumbone are diverse, encompassing various fields of scientific research, particularly in pharmacology and medicinal chemistry. It has exhibited significant potential as an anti-cancer agent, showing efficacy in inhibiting the proliferation of several cancer cell lines. Additional investigations have highlighted its anti-inflammatory, antioxidant, and antimicrobial properties. Due to these multifaceted bioactivities, Zerumbone is a subject of extensive study as a template for the synthesis of novel compounds with enhanced therapeutic indices. Its promise in therapeutics paves the way for further exploration in drug development and clinical applications.

Alicyclic ketone

Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z.

Zerumbone analytical standard provided with w/w absolute assay, to be used for quantitative titration.