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CAS 472-26-4: Telocinobufagin

Formula:C24H34O5
InChI:InChI=1S/C24H34O5/c1-21-9-5-16(25)13-23(21,27)11-7-19-18(21)6-10-22(2)17(8-12-24(19,22)28)15-3-4-20(26)29-14-15/h3-4,14,16-19,25,27-28H,5-13H2,1-2H3/t16-,17+,18-,19+,21+,22+,23-,24-/m0/s1
InChI key:InChIKey=PBSOJKPTQWWJJD-ZBDZJSKLSA-N
SMILES:O[C@@]12[C@]3([C@@]([C@]4(C)[C@](O)(CC3)C[C@@H](O)CC4)(CC[C@]1(C)[C@H](CC2)C=5C=CC(=O)OC5)[H])[H]
Synonyms:
  • (3Beta,5Beta)-3,5,14-Trihydroxybufa-20,22-Dienolide
  • (3β,5β)-3,5,14-Trihydroxybufa-20,22-dienolide
  • 3Β,5,14-Trihydroxy-5Β-Bufa-20,22-Dienolide
  • 5.beta.-Bufa-20,22-dienolide, 3.beta.,5,14-trihydroxy-
  • 5β-Bufa-20,22-dienolide, 3β,5,14-trihydroxy-
  • Bufa-20,22-Dienolide, 3,5,14-Trihydroxy-, (3Beta,5Beta)-
  • Bufa-20,22-Dienolide, 3,5,14-Trihydroxy-, (3Beta,5Beta,8Xi,9Xi)-
  • Bufa-20,22-dienolide, 3,5,14-trihydroxy-, (3.beta.,5.beta.)-
  • Bufa-20,22-dienolide, 3,5,14-trihydroxy-, (3β,5β)-
  • NSC 119989
  • NSC 90782
  • See more synonyms
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Found 6 products.
  • Telocinobufogenin
    TRC
    + Info

    Telocinobufogenin

    Controlled Product
    CAS:
    Applications Telocinobufagin is isolated as a major component from skin secretion of the toad Bufo rubescens. Telocinobufogenin is a novel antibiotic cardiotonic. References Akizawa, T., et al.: Chem. Pharm. Bull., 42, 754 (1994); Hancock, R., et al.: Antimicrob. Agents Chemother., 43, 1317 (1999); Jing, Y., et al.: J. Cancer Res., 85, 645 (1994); Kamano, Y., et al.: J. Med. Chem., 45, 5440 (2002); Schoner, W., et al.: Eur. J. Biochem., 269, 2440 (2002); Cunha Filho, G., et al.: Toxicon, 45, 777 (2005)
    Formula:C24H34O5
    Color and Shape:Neat
    Molecular weight:402.52

    Ref: TR-T017060

    25mg
    2,264.00€
    2500µg
    337.00€
  • Telocinobufagin
    Targetmol
    + Info

    Telocinobufagin

    CAS:
    Telocinobufagin, a potent digitalis-like factor, reduces spleen bacteria and boosts survival in immunized mice, showing promise as an immunotherapy for cancer.
    Formula:C24H34O5
    Purity:98.42% - 99.74%
    Color and Shape:Solid
    Molecular weight:402.52

    Ref: TM-T4A2462

    1mg
    63.00€
    5mg
    137.00€
    10mg
    210.00€
    25mg
    375.00€
    50mg
    550.00€
    100mg
    783.00€
    1mL*10mM (DMSO)
    153.00€
  • Telocinobufagin
    Glentham
    + Info

    Telocinobufagin

    CAS:
    Formula:C24H34O5
    Molecular weight:402.53

    Ref: 7W-GY7301

    ne
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  • Telocinobufagin
    Biosynth
    + Info

    Telocinobufagin

    CAS:
    Telocinobufagin is a natural compound that inhibits the proliferation of cancer cells by binding to the cell nucleus. It also has a matrix effect on the mesenchymal cells in cancer tissues, which may be due to its ability to regulate the physiological effects of these cells. Telocinobufagin has been shown to inhibit apoptosis in HL-60 cells and other cell lines by inducing DNA fragmentation, chromatin condensation, and activation of caspase-3. This process is triggered by mitochondrial membrane potential disruption or induction of Bax protein expression.
    Formula:C24H34O5
    Purity:Min. 95%
    Molecular weight:402.52 g/mol

    Ref: 3D-FT74164

    1mg
    Discontinued
    2mg
    Discontinued
    5mg
    Discontinued
    10mg
    Discontinued
    25mg
    Discontinued
    Discontinued product
  • 3β,5,14-Trihydroxy-5β-bufa-20,22-dienolide
    Indagoo
    + Info

    3β,5,14-Trihydroxy-5β-bufa-20,22-dienolide

    CAS:
    Formula:C24H34O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.5238

    Ref: IN-DA00DB9A

    5mg
    174.00€
    10mg
    259.00€
  • Telocinobufagin
    Biopurify
    + Info

    Telocinobufagin

    CAS:
    Telocinobufagin (TCB), a bufadienolide extracted from Bufo paracnemis parotoid glands, shows a reversible local anesthetic action, similar to BUPI, however, without cardiac toxicity in vitro.
    Formula:C24H34O5
    Purity:95%~99%
    Color and Shape:Powder
    Molecular weight:402.531

    Ref: BP-BP1370

    10mg
    112.00€
    20mg
    187.00€
    100mg
    530.00€