CAS 475-83-2: Nuciferine

Nuciferine possesses anti-diabetic, anti-obesity, anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, vasorelaxant, and insulin secretagogue activities. Nuciferine may be potential for the prevention and treatment of hyperuricemia with kidney inflammation. It inhibited tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer.

(R)-1,2-Dimethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinoline

Nuciferine is a natural alkaloid, which is derived from the leaves of the sacred lotus plant, Nelumbo nucifera. This compound exhibits a diverse range of pharmacological activities due to its interaction with various receptors and enzymes within the human body. Known for its antagonist activity on certain serotonin and dopamine receptors, nuciferine influences neurotransmitter pathways, which contributes to its potential therapeutic effects. Nuciferine has been investigated for its applications in various medical fields due to its wide-ranging biological effects, including anti-inflammatory, antipsychotic, and anti-obesity properties. Research indicates that it might play a role in modulating lipid metabolism and could contribute to cardiovascular health. Additionally, its potential impact on neuropharmacological systems offers promise for mental health applications. Scientists are particularly interested in its ability to influence metabolic and neuronal pathways, making it a subject of ongoing research in both pharmacology and biochemistry.

Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera.

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Applications Nuciferin is an drug candidate for the treatment of obesity-related diseases. It is not well studied and its pharmacokinetics in vivo have not been fully investigated. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gu, S. et al.: J. Chrom. B. Anal. Tech. Biomed. Life Sci., 961, 20 (2014);

Nuciferine

Natural alkaloid