Guanosine-5',5'-C-d2, monohydrate (CAS 478511-34-1) is a modified nucleoside that features deuterium substitution at the 5' carbon position of the guanosine molecule. This compound is characterized by its role in biochemical research, particularly in studies involving nucleic acid metabolism and the dynamics of RNA. The presence of deuterium, a stable isotope of hydrogen, allows for enhanced analytical techniques such as NMR spectroscopy, enabling researchers to trace metabolic pathways and interactions more effectively. As a monohydrate, it contains one molecule of water per molecule of guanosine, which can influence its solubility and stability. Guanosine itself is a purine nucleoside composed of a guanine base attached to a ribose sugar, playing a crucial role in cellular processes, including energy transfer and signal transduction. The specific isotopic labeling and hydration state of Guanosine-5',5'-C-d2 make it a valuable tool in molecular biology and biochemistry for studying nucleic acid structures and functions.

Guanosine-5',5'-C-d2,monohydrate (9CI)

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Stability Hygroscopic
Applications Isotope labelled analogue of Guanosine (G837900), a constituent of nucleic acids.
 Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Miles, et al.: Science, 142, 1458 (1963), Bugg, et al.: Biochem. Biophys. Res. Commun., 3, 436 (1968),


CAS 478511-34-1: Guanosine-5',5'-C-d2,monohydrate (9CI)

Guanosine-5',5''-d2 Monohydrate

Ref: TR-G837915