L-Glucose-1-13C (9CI) is a stable isotope-labeled form of L-glucose, where the carbon atom at position 1 is replaced with the carbon-13 isotope. This modification allows for enhanced tracking and analysis in various biochemical and metabolic studies, particularly in research involving carbohydrate metabolism and flux analysis. L-Glucose itself is an epimer of D-glucose, differing in the configuration around the first carbon atom, which influences its biological activity and interaction with enzymes and transporters. The presence of the carbon-13 isotope does not significantly alter the chemical properties of L-glucose, but it provides a valuable tool for nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry applications. This compound is typically used in research settings, particularly in studies related to metabolic pathways, and can be utilized in tracer studies to investigate glucose metabolism in living organisms. As with many isotopically labeled compounds, L-Glucose-1-13C is handled with care in laboratory settings to ensure accurate results and safety.

L-Glucose-1-13C (9CI)

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Applications Labelled L-Glucose is the enantiomer of D-Glucose (G595000), a naturally occurring carbohydrate used in an abundance of cellular processes. L-Glucose is a synthetic sugar used in the formation of L-Glucose Pentaacetate (G596510), a potential therapeutic agent regarding type II diabetes. In addition, L-glucose can be used as a colon cleansing agent for before a colonoscopy procedure.
References Malaisse, W. et al.: Int. J. Mol. Med., 2, 383 (1998); Raymer, G. et al.: Gastrointest. Endosc., 58, 30 (2003); Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009),


CAS 478519-02-7: L-Glucose-1-13C (9CI)

L-Glucose-1-13C

Ref: TR-G596506