CAS 482376-13-6: 4-(chloromethyl)-2-(4-fluorophenyl)pyridine

4-(Chloromethyl)-2-(4-fluorophenyl)pyridine is a compound that has been shown to have potential use in bladder cancer. It is currently under investigation and not yet approved for clinical use. This drug binds to the toll-like receptor 4 (TLR4) on cancer cells, which triggers a proinflammatory response. TLR4 activation induces the production of cytokines such as IL-6, IL-8, and TNF-α by tumor cells, leading to increased inflammation in the bladder. 4-(Chloromethyl)-2-(4-fluorophenyl)pyridine also inhibits muscle cell proliferation and causes malignant changes in bladder cells. The compound has been shown to be effective against muscle tissue, but not nonmuscle tissue.