
CAS 483-17-0: (-)-Cephaeline
Formula:C28H38N2O4
InChI:InChI=1S/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20-,23+,24-/m0/s1
InChI key:InChIKey=DTGZHCFJNDAHEN-OZEXIGSWSA-N
SMILES:C([C@H]1C[C@]2(C=3C(=CC(OC)=C(OC)C3)CCN2C[C@@H]1CC)[H])[C@@H]4C=5C(=CC(O)=C(OC)C5)CCN4
Synonyms:- (1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol
- (2Xi)-7',10,11-Trimethoxyemetan-6'-Ol
- 6-Isoquinolinol, 1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-, (1R)-
- 7',10,11-Trimethoxyemetan-6'-Ol
- 7′,10,11-Trimethoxyemetan-6′-ol
- Cephalin (animal)
- Cepheline
- Desmethylemetine
- Dihydropsychotrine
- Emetan-6′-ol, 7′,10,11-trimethoxy-
- Cephaeline
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Cephaeline
CAS:Cephaeline is an alkaloid compound, which is extracted from the roots of the ipecac plant, Psychotria ipecacuanha. It exhibits its primary mode of action by stimulating the chemoreceptor trigger zone in the brain, leading to a pronounced emetic effect. This mechanism activates the vomiting reflex, an action that also simultaneously stimulates bronchial secretions. The primary applications of Cephaeline have historically been in the medical field, notably as a component in emetic formulations intended to induce vomiting in cases of poisoning. However, its role extends beyond emesis; it is also recognized for its potential as an expectorant, aiding in the clearance of mucus from the respiratory tract during respiratory infections. While its use as a therapeutic agent in modern medicine has diminished due to the discovery of more effective and safer alternatives, it remains a compound of interest in phytochemical studies and the development of botanical extracts. Scientists are continually exploring its pharmacological potentials and safety profile.Purity:Min. 95%Color and Shape:Yellow To Orange SolidMolecular weight:466.61Cephaeline Hydrobromide
CAS:Controlled ProductStability Hygroscopic Applications Hydrobromide Salt of Cephaeline (C256700), used as an emetic and expectorant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Crouch, D.J., et al.: J. Anal. Toxicol., 8, 63 (1984), Guengerich, F., et al.: Pharmacol. Ther., 54, 17 (1992), Myers, C., et al.: Environ. Toxicol. Chem., 13, 461 (1994),Formula:C28H38N2O4·BrHPurity:>90%Color and Shape:NeatMolecular weight:547.52Cephaeline
CAS:Cephaeline: active on CLL cells (IC50: 35nM), inhibits HIF-1α, disrupts redox balance.Formula:C28H38N2O4Purity:99.45% - 99.88%Color and Shape:SolidMolecular weight:466.61