CAS 483367-10-8: Purmorphamine
Formula:C31H32N6O2
InChI:InChI=1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)
InChI key:InChIKey=FYBHCRQFSFYWPY-UHFFFAOYSA-N
SMILES:N(C1=C2C(N(C=N2)C3CCCCC3)=NC(OC=4C5=C(C=CC4)C=CC=C5)=N1)C6=CC=C(C=C6)N7CCOCC7
Synonyms:- 2-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
- 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
- 9H-Purin-6-amine, 9-cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-
- Purmorphamine
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Found 8 products.
Purmorphamine
CAS:Controlled ProductApplications Activates the Hedgehog pathway. References Cooper, M., et al.: Science, 280, 1603 (1998), Ingham, P., et al.: Genes Dev., 15, 3059 (2001), Beachy, P., et al.: Nature, 432, 324 (2004), Wu, X., et al.: Chem. Biol., 11, 1229 (2004),Formula:C31H32N6O2Color and Shape:NeatMolecular weight:520.62Purmorphamine
CAS:Formula:C31H32N6O2Purity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:520.64Purmorphamine
CAS:Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.Formula:C31H32N6O2Purity:97.19% - 99.48%Color and Shape:Light Tan SolidMolecular weight:520.62Purmorphamine
CAS:Purmorphamine is a cell factor that belongs to the group of morphogens. It is structurally related to dopamine and has been shown to be effective in the treatment of Parkinson's disease. Purmorphamine is involved in the regulation of neuronal survival, differentiation, proliferation, and axon guidance. Purmorphamine binds to a receptor on neurons called the cholinergic receptor, which stimulates a G-protein linked signal transduction pathway. This leads to an increase in intracellular calcium levels and activation of protein kinase C. Purmorphamine also has anti-inflammatory effects and can inhibit leukemia inhibitory factor (LIF). It has been shown to be effective against LPS-induced inflammatory responses by inhibiting protein synthesis. Purmorphamine also inhibits cancer cells through its ability to stimulate growth factor-β1 (GF-β1) gene expression.Formula:C31H32N6O2Purity:Min. 95%Color and Shape:PowderMolecular weight:520.63 g/mol
