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CAS 490-82-4: 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-2(3H)-thiazolone
Formula:C12H16N4O2S
InChI:InChI=1S/C12H16N4O2S/c1-7-10(3-4-17)19-12(18)16(7)6-9-5-14-8(2)15-11(9)13/h5,17H,3-4,6H2,1-2H3,(H2,13,14,15)
InChI key:InChIKey=VXCONGLPCAPYEU-UHFFFAOYSA-N
SMILES:C(N1C(C)=C(CCO)SC1=O)C=2C(N)=NC(C)=NC2
Synonyms:- (3H)-Thiazolone, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-
- 2(3H)-Thiazolone, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-
- 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-(3H)-thiazolone
- 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolin-2-one
- 3-((4-Amino-2-metil-5-pirimidinil)metil)-5-(2-idrossietil)-4-metiltiazolin-2-one
- 3-((4-Amino-2-metil-5-pirimidinil)metil)-5-(2-idrossietil)-4-metiltiazolin-2-one [Italian]
- 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-2(3H)-thiazolone
- 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2(3H)-one
- 4-Thiazolin-2-one, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-
- Brn 0310984
- Thiamin thiazolone
- See more synonyms
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Found 5 products.
Oxo Thiamine
CAS:Applications Thiamine (T344185) impurity. References Warnock, L., et al.: Anal. Biochem., 126, 394 (1982), Royer-Morrot, J., et al.: Eur. J. Clin. Pharmacol., 42, 219 (1992),Formula:C12H16N4O2SColor and Shape:Off-WhiteMolecular weight:280.35Thiamine EP Impurity D (Oxo Thiamine)
CAS:Formula:C12H16N4O2SColor and Shape:White To Off-White SolidMolecular weight:280.353-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazol-2(3H)-one
CAS:Formula:C12H16N4O2SPurity:95%Color and Shape:SolidMolecular weight:280.346Oxo thiamine
CAS:Oxo thiamine (OT) is a group II intramolecular hydrogen donor that has been shown to be effective against various types of cancer. OT is a competitive inhibitor of the bacterial enzyme sulfamidase, which is responsible for hydrolyzing sulfamethoxazole resulting in resistance to this antibiotic. In addition, OT inhibits mitochondrial complex I and causes a loss in mitochondrial membrane potential. OT also has anti-inflammatory properties and can be used as an analog in nuclear DNA synthesis. OT binds to the nitrogen atom on the phosphate group of ATP and forms a hydrogen bond with the oxygen atom on the same phosphate group, inhibiting enzymatic reactions.Formula:C12H16N4O2SPurity:Min. 95%Color and Shape:White PowderMolecular weight:280.35 g/mol
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